Curriculum Vitae
 
Perinatal Services 

Douglas A. Milligan, M.D.

John Michael O'Brien Jr., M.D.

John Robert Barton, M.D.



DOUGLAS A. MILLIGAN, M.D.
 Dr. Milligan
Business Address
Office Central Baptist Hospital
Perinatal Diagnostic Center
1740 Nicholasville Road
Lexington, KY 40503
(859) 260-6970
Education
1973-77 The Johns Hopkins University Baltimore, Maryland Undergraduate B.A. Degree, Natural Sciences
1978-82 University of Colorado School of Medicine Denver, Colorado Medical M.D. Degree (Alpha Omega Alpha)
Postgraduate Training
1982-83 Madigan Army Medical Center Tacoma, Washington Categorical Ob/Gyn Internship
1983-86 Madigan Army Medical Center Tacoma, Washington Obstetrical-Gynecologic Residency
1988-90 Madigan Army Medical Center Maternal-Fetal Medicine Fellowship
1985 Chemical Casualty Care Course
1989 Combat Casualty Care Course
Military Service
1977-82 Medical Service Corps
1982-92 Medical Corps
Certification
1983 National Board of Medical Examiners, Diplomate #271332
1985, 1991 Advanced Cardiac Life Support
1989 Advanced Trauma Life Support
1988 Board Certified, American Board of Obstetrics and Gynecology
1992 Certificate of Special Competence in Maternal-Fetal Medicine, American Board of Obstetrics and Gynecology Division of Maternal-Fetal Medicine
Professional Society Memberships
1988 Fellow, American College of Obstetricians and Gynecologists
1988 Society of Perinatal Obstetricians
1981 Alpha Omega Alpha Honorary Medical Society
Honors and Awards
1977 Thomas Arkle Clark National Leadership Award, Alpha Tau Omega Fraternity
1981-82 University of Colorado School of Medicine, Admission Committee Service Award
1982 Alpha Omega Alpha
Publications
  1. Duff P, Harlass FE, Milligan DA. Prenatal Diagnosis of Chondrodysplasia Punctata by Sonography. Obstet Gynecol 1990;73(2):497-500.
  2. Milligan DA, Duff P, Brady WK. Clinical Course and Efficacy of Short Course Therapy of Puerperal Endometritis. Journal of Maternal-Fetal Medicine 1992;1:60-63.
  3. Milligan DA, Duff P. Puerperal Mastitis. In Pastorek JG, ed. Infectious Disease in the Female. New York, Aspen Press, 1991 press.
  4. Milligan DA, Harlass FE, Duff P, Kopelman JN. Recurrence of Treacher Collins' Syndrome with Sonographic Findings. Military Medicine, in press.
  5. Yancey MK, Moore J, Brady WK, Milligan DA, Strampel W. The Effect of Altitude on Umbilical Cord Gases. Obstet Gynecol, in press.
  6. Fontenot MT, Lameier L, Porter WH, Mitchell-Tutt E, Read JA, Milligan DA, Campbell BA. Comparison of spot urine protein index and quantitative 24-hour urinary protein excretion in pregnancy. Submitted to Am J Ob/Gyn, February 1996.
  7. Fontenot MT, Campbell BA, Mitchell-Tutt E, Read JA, Milligan DA, Miller FC, Lewis DF. Radiographic evaluation of breech presentation: Is it necessary? Submitted to Am J Ob/Gyn, February 1996.
  8. Campbell BA, Fontenot MT, Read JA, Milligan DA, Mitchell-Tutt E, Crowe S. Newman RB. Is the routine use of nonstress testing necessary in twin gestations? Submitted to Am J Ob/Gyn, February 1996.
  9. O'Brien JM, Milligan DA, Barton JR. The Impact of High Dose Corticosteroid Therapy in Patients with Hemolysis, Elevated Liver Enzymes and Low Platelet Count (HELLP Syndrome). Am J Obstet Gynecol 2000, in press.
Abstracts and Presentations
  1. Milligan DA, Watson WJ, Read JA. Pregnancy Outcome in Patients Admitted with Hyperemesis Gravidarum. Presented at the 23rd Annual AFD-ACOG, Atlanta, GA, 1984.
  2. Milligan DA, Duff P, Read JA. Acute Urinary Retention in Early Pregnancy Secondary to Incarcerated Uterus. Presented at the 24th Annual AFD-ACOG, New Orleans, LA, 1985.
  3. Milligan DA. Chronic Spinal Headache After Cesarean Section, a Case Report and Review of the Literature. Presented at the 26th Annual AFD-ACOG, Denver, CO, 1987.
  4. Milligan DA, Watson WJ. Nephrolithiasis in Pregnancy. Presented at the 26th Annual AFD-ACOG, Denver, CO, 1987.
  5. Milligan DA, Duff P. Short Course Therapy for Endomyometritis. Presented at the 28th Annual AFD-ACOG, Washington, DC, 1989.
  6. Yancey MK, Moore J, Brady WK, Milligan DA, Strampel W. The Effect of Altitude on Umbilical Cord Blood Gases. Presented at Society of Perinatal Obstetricians, Orlando, FL, 1992.
  7. Fontenot T, Lameier L, Milligan D, Read JA, Miller F, Poerter W, Mohapatra A, Tutt E, Campbell B. Comparison of urine protein index and quantitative 24-hour urinary protein excretion. Abstract #107. Society of Perinatal Obstetricians 16th Annual Meeting, Kamuela, Hawaii, February 1996. (Am J Ob/Gyn 1996;174(2):342).
  8. Fontenot T, Lewis D, Campbell B, Milligan D, Tutt E, Read J, Miller F. Radiographic evaluation of breech presentation: Is it necessary? Abstract #108. Society of Perinatal Obstetricians 16th Annual Meeting, Kamuela, Hawaii, February 1996. (Am J Ob/Gyn 1996;174(2):342).
  9. Campbell B, Fontenot T, Read J, Milligan D, Tutt E, Crowe S, Newman R. Is the routine use of non stress testing necessary in twin gestations? Abstract #93. Society of Perinatal Obstetricians 16th Annual Meeting, Kamuela, Hawaii, February 1996. (Am J Ob/Gyn 1996;174(2):339).
  10. O'Brien JM, Barton JR, Milligan DA. Corticosteroid Dosing and Laboratory Changes in Patients with Hemolysis, Elevated Liver Enzymes and Low Platelet Count (HELLP Syndrome). Society for Maternal-Fetal Medicine, 20th Annual Meeting, Miami Beach FL, February 2000. (Am J Obstet Gynecol 2000:182[1(pt2)]:
  11. O'Brien JM, Barton JR, Shumate SA, Satchwell SL, Milligan DA. The Impact of Corticosteroid Administration on the Rate of Regional Anesthesia in Patients with Hemolysis, Elevated Liver Enzymes and Low Platelet Count (HELLP Syndrome). Society for Obstetric Anesthesia and Perinatology, 32nd Annual Meeting, Montreal, QC Canada, June 2000.
  12. Barton JR, O'Brien JM, Milligan DA. Management and Outcome of Pregnancies Complicated by HELLP Syndrome: A Community Hospital Perspective. XIIth World Congress on Hypertension in Pregnancy, Paris, France, July 200.
  13. Barton JR, Bush K, O'Brien JM, Milligan DA. The Impact of High Dose Corticosteroid on Laboratory Changes in Women with Hemolysis, Elevated Liver Enzymes and Low Platelet Count (HELLP Syndrome). XIIth World Congress on Hypertension in Pregnancy, Paris, France July 2000.
  14. Barton JR, Shumate SA, O'Brien JM, Satchwell SL, Milligan DA. The Impact of Corticosteroid Administration on the Rate of Regional Anesthesia in Patients with Hemolysis, Elevated Liver Enzymes and Low Platelet Count (HELLP Syndrome). XIIth World Congress on Hypertension in Pregnancy, Paris, France July 2000.
Articles and Abstracts Currently under Review
  1. O'Brien JM, Shumate SA, Satchwell SL, Milligan DA, Barton JR. The Impact of Corticosteroid Administration on the Rate of Regional Anesthesia in Patients with Hemolysis, Elevated Liver Enzymes and Low Platelet Count (HELLP syndrome). Submitted to Anesthesia.
  2. O'Brien JM, Barton JR, Milligan DA. The Diagnosis and Time Course of Pancreatitis in Association with Acute Fatty Liver of Pregnancy. Submitted to the Society of Maternal-Fetal Medicine, 21st Annual Meeting, Reno, NV, February 2001.
Lectures
March, 1992 Ultrasound Screening for Chromosomal Abnormalities
7th MEDCOM Ob/Gyn Conference
Willingen, Germany
March, 1992 Clinical Management of Macrosomia
7th MEDCOM Ob/Gyn Conference
Willingen, Germany
March, 1992 Management Controversies of ITP in Pregnancy
7th MEDCOM Ob/Gyn Conference
Willingen, Germany
March, 1992 Cardiomyopathy in Pregnancy
7th MEDCOM Ob/Gyn Conference
Willingen, Germany
March, 1992 Fetal Oncogenes as Predictors of Preterm Delivery
Born to Soon, PSL Conference
Denver, Colorado
August, 1992 Surfactant Induction
Department of Obstetrics and Gynecology
Aurora Presbyterian Hospital
Aurora, Colorado
November, 1992 Assessment of Well-being in the Preterm Fetus
Prematurity Prevention Conference
Denver, Colorado
April, 1993 Screening for Trisomy 21 in the Low Risk Population
Lutheran Medical Center Grand Rounds
Denver, Colorado
May, 1993 Uterine Abnormalities and Reproductive Risks
TOCOS Payor Breakfast
Denver, Colorado

University of Kentucky Family Medicine Lectures
Revised 6/07/00


John Michael O'Brien Jr., M.D.
 Dr. OBrien
Business Address
Office Director, Perinatal Diagnostic Center
Central Baptist Hospital
1740 Nicholasville Road
Lexington, KY 40503
(606) 260-6970, fax 2605-6649
Education
Undergraduate Kalamazoo College, Kalamazoo, MI
1980-1984
B.A. in Biology with Honors, June 1984
Graduate/Medical School Wayne State University School of Medicine
1980-1984
M.D., June 1988
Internship/Residency Obstetrics and Gynecology
Wayne State University affiliated Hospitals Program, Detroit, MI
July 1988-June 1992
Fellowship Maternal-Fetal Medicine
Department of Obstetrics and Gynecology
University of Tennessee, Memphis, TN
July 1992-June 1994
Board Certification:
Obstetrics and Gynecology Diplomate, November 1995.
Maternal-Fetal Medicine Board certified, April 1997.
Society Memberships
  • American College of Obstetrics and Gynecology (ACOG), Fellow
  • Society of Maternal Fetal Medicine (SMFM), Regular Member
  • International Society of Ultrasound in Obstetrics and Gynecology
  • American Institute of Ultrasound in Medicine
  • Central Association of Obstetricians and Gynecologists
  • American Medical Association
  • Kentucky Medical Association
  • Fayette County Medical Association
  • Lexington Obstetrics and Gynecology Society
Hospital Appointments
Director, Perinatal Diagnostic Center, July 1994 to present
Department of Obstetrics and Gynecology,
Central Baptist Hospital, Lexington, Kentucky

Chairman, Peer Review Committee, Central Baptist Hospital
Department of Obstetrics and Gynecology
Other Appointments
Department of Obstetrics and Gynecology, University of Kentucky,
Part-time Faculty, 1996 to present

Commonwealth of Kentucky, Birth Defects Surveillance Registry Advisory
Committee, November 1999 to present
Funded Research
Title: A Phase III Randomized Placebo-Controlled Trial to Evaluate the Efficacy,
Safety and Tolerance of Oral Zidovudine (ZDV) in Pregnant HIV Infected
Women and their Infants (076 Trial)
Investigator: Site Collaborating Investigator
Date: January 1993-March 1994
Funding: The National Institute of Allergy and Infectious Disease
AWARDS
Joan C. Stryker Award for Medical Student Education, 1989.
Publications - Peer Review Articles:
  1. Neonatal progeroid (Wiedemann-Rautenstrauch) syndrome: report of five new cases and review. Pivnick EK, Angle B, Kaufman RA, Hall BD, Pitukcheewanont P, Hersh JH, Fowlkes JL, Sanders LP, O'Brien, JM, Carroll GS, Gunther WM, Morrow HG, Burghen GA, Ward JC. Am J Genet 2000:90;131-40.
  2. The Use of Contrast for Endovaginal Sonography in the Obstetrical Patient. O'Brien, JM, Allen A, Barton JR, Ultrasound in Obstetrics and Gynecology, 1999:13;137-9
  3. The Management of Placenta Percreta: Conservative and Operative Strategies. O'Brien JM, Barton JR, Donaldson E. Am J Obstet Gynecol. 1996:175;1632-8.
  4. The Efficacy of Outpatinet Induction with Low Dose Intravaginal Prostaglandin E2: A Randomized, Double-Blind, Placebo-Controlled Trial. O'Brien JM, Mercer B, Cleary N. Sibai BM. Am J Obstet Gynecol 1995: 173;1885-9.
  5. The Impact of Initiating an HIV Screening Program in an Urban Obstetric Population. Lewis R, O'Brien, JM, Ray D, Sibai BM. Am J Obstet Gynecol 1995: 173; 1329-34.
  6. Early versus Late Amniotomy for Labor Induction: A Randomized Trial. Mercer BM, McNanley T, O'Brien JM, Randal L, Sibai BM. Am J Obstet Gynecol 1995: 173;1321-5.
  7. Daily Antenatal Testing in Patients with Severe Preeclampsia. Chari RS, Friedman SA, O'Brien JM, Sibai BM. Am J Obstet Gynecol 1995; 173: 1207-11.
  8. The use of a Modified Vaginal Pouch for the Diagnosis and Management of Preterm Premature Rupture of the Fetal Membranes. O'Brien JM, Mercer BM, Sibai BM. Am J Obstet Gynecol 1995; 173: 1565-6.
  9. Cervicovaginal Prolactin: A Marker for Spontaneous Preterm Delivery. O'Brien JM, Peeler GH, Pitts DW, Salama M, Sibai BM, Mercer BM. Am J Obstet Gynecol 1994; 171: 1107-11.
  10. Amniotic Fluid Index in Hospitalized Hypertensive Patients Managed Expectantly. O'Brien JM, Mercer BM, Friedman SA, Sibai BM. Obstet Gynecol 1993; 82: 247-250.
  11. Vaginal Delivery of a Second, Nonvertex Twin by High Vacuum After Failed Breech Extraction and Successful External Version. O'Brien JM and Shaver DC. J Maternal-Fetal Med 1993; 2:243-245
  12. Maternal and Neonatal Primary Hemostasis. Saleh AA, Delozier DE, Duchon TA, O'Brien JM, Munkarah AM, Kazzi GM, Mammen E. Throm Res 1993; 73(2): 125-129.
  13. The Sonographically Thick Placenta: A Predictor of Increased Perinatal Morbidity and Mortality. Dombrowski MP, Wolfe HM, Saleh AA, Evans MI, O'Brien J, Ultrasound Obstet Gynecol 1992; 2(4): 252-255.
  14. Inihibition of Rat Liver Glutathione S-Transferases by Piriprost: Kinetics of the Inhibition and Preliminary Evidence that Piriprost May be a Poor Alternate Substrate for these Enzymes. Bach MK, O'Brien JM, Brashler J, et al. Res Com Chem Path and Pharm 1985; 49(3): 361-386.
  15. Identification of a Trans-dominant Mutation Affecting Proline Dehydrogenase in Escherichia Coli. Deutch C, O'Brien and VanNieuwenhze M. Can J Micro 1985; 31: 988-993.
Publications - Book Chapters
  1. O'Brien JM. The Pneumonias. In: Medical Complications of Pregnancy, third edition. Gleicher N, Gail SA, Sibai BM, Elkayam U, Galbraith RM, Sarto GE (eds). Appleton and Lange, Chap 133, pp 888-892.
  2. O'Brien JM. Postpartum Hemorrhage. In: Practical Guide to the Care of the Gynecologic/Obstetric Patient. Danakas GT and Pietantoni M (eds). Mosby-Year Book, Inc. Chap 31, pp 805-12, 1997.
Selected Abstracts
  1. Intraamniotic Administration of Purine Nucleotides Stimulates Ovine Surfactant Secretion. O'Brien JM, Mercer BM, Beegle BE, Mandrel TD, Sibai BM. Presentation to the 1995 Annual Meeting of the Society of Perinatal Obstetricians.
  2. Factors Associated with Early and Late Midtrimester PROM. BM Mercer, NL Meyer, JM O'Brien, NL Meyer, LW Livingston, BM Sibai. Abstract presented to the 2000 Annual Meeting of the Society of Maternal-Fetal Medicine.
  3. Outcomes of Midtrimester PROM at the End of the 20th Century. BM Mercer, JM O'Brien, NL Meyer, LW Livingston, BM Sibai. Abstract presented to the 2000 Annual Meeting of the Society of Maternal-Fetal Medicine.
  4. Management and Outcome of Pregnancies Complicated by HELLP Syndrome Cared for in a Community Hospital. Barton JR, O'Brien JM, Campbell BA. Presentation to the 1999 Central Association of Obstetrician and Gynecologists Annual Meeting.
  5. Mild Preeclampsia Remote from Term: Progression and Outcome. Barton JR, O'Brien JM, Bergauer NK, Jacques DL, Sibai BM. Presentation to the 1999 Annual Meeting of the Society of Maternal Fetal Medicine.
  6. Does a Low Prepregnancy Body Mass Index Influence in Pregnancies Complicated by Mild Preeclampsia Remote from Term? Barton JR, O'Nan JM, O'Brien JM, Bergauer NK, Jacques DL, Sibai BM. Presentation to the XI World Congress on Hypertension in Pregnancy, 1998.
  7. The Impact of Gestational Order on Baseline Uterine Activity. O'Brien JM, Barton JM, Bergauer NK, Jacques DL, Stanziano GJ. Presentation to the 1998 Annual Meeting of the Society of Perinatal Obstetricians.
  8. Cervical Width and Cervical Stromal Width Vary in Patients with Cervical Insufficiency. O'Brien JM, AA Allen, Barton JM. Presentation to the 1998 Annual Meeting of the Society of Perinatal Obstetricians.
  9. Does Pre-pregnancy Body Mass Index Influence Outcome in Pregnancies complicated by Mild Pre-eclampsia Remote from Term. Barton JM, O'Brien JM, Bergauer NK, Jacques DL, Stanziano GJ. Presentation to the 1998 Annual Meeting of the Society of Perinatal Obstetricians.
  10. Newborn Hospitalization and Birth Weight Differences Related to Maternal Diagnosis at Time of Preterm Delivery. Barton JM, O'Brien JM, Bergauer NK, Jacques DL, Stanziano GJ, Sibai BM. Presentation to the 1998 Annual Meeting of the Society of Perinatal Obstetricians.
  11. Intravaginal Normal Saline as a Contrast Agent for Cervical Sonography. O'Brien JM, AA Allen, Barton JM. Presentation to the 1998 Annual Meeting of the Society of Perinatal Obstetricians.
  12. Cervical Width and Cervical Gland Width Vary Throughout Gestation. O'Brien JM, AA Allen, Barton JM. Presentation to the 1997 Annual Meeting of the Society of Perinatal Obstetricians.
  13. Contraction Frequency and Premature Delivery in Twin, Triplet and Quadruplet Gestations. O'Brien JM, Barton JM, Bergauer NK, Jacques DL. Presentation to the 1997 Annual Meeting of the Society of Perinatal Obstetricians.
  14. Platelet Count: The Bellwether of Maternal and Neonatal Outcome ni Severe Preeclampsia. Barton JR, O'Brien JM, Audibert F, Friedman SA, Sibai BM. Presentation to the 1997 Annual Meeting of the Society of Perinatal Obstetricians.
  15. Uterine Activity in Pregnancies Complicated by Polyhydramnios. O'Brien JM, Bergauer NK, Jacques DL. Presentation to the 1997 Annual Meeting of the American College of Obstetricians and Gynecologists.
  16. The Indications for Cervical Cerclage. O'Brien JM, Bergauer NK, Jacques DL. Presentation to the 1997 Annual Meeting of the American College of Obstetricians and Gynecologists.
  17. The Utility of Prophylactic Cerclage in Triplet Pregnancy. O'Brien JM, Jacques DL, Bergauer NK, Stanziano GJ, Sibai BM. Presentation to the 1996 Society of Perinatal Obstetricians meeting.
  18. Perinatal Outcome in Quadruplet Gestations. Barton JR, O'Brien JM, Jacques DL, Bergauer NK, Stanziano GJ, Sibai BM. Presentation to the 1996 Society of Perinatal Obstetricians meeting.
  19. In Utero Treatment of Right-sided Congenital Diaphramatic Hernia (R-CDH) by Prenatal Tracheal Occlusion. Flake AW, Johnson MP, Treadwell M, Mason B, Cauldwell C, Phillipart AI, Cullen ML, O'Brien J, Adzick NS, Harrison MR, Evans MI. Presentation to the 1996 Society of Perinatal Obstetricians Meeting.
  20. Efficacy of Outpatient Induction with Low Dose Intravaginal Prostaglandin E2: A Randomized, Double-Blind, Placebo-Controlled Trial. O'Brien JM, Mercer B, Clary N, Sibai BM. Presentation at the 1995 Annual Meeting of the Society of Perinatal Obstetricians.
  21. A Comparison of Fetal Fibronectin, Prolactin, and Cervical Examination for the Prediction of Preterm Delivery in Symptomatic Patients. O'Brien JM, Mercer B, Pitts DW, Sibai BM. Presentation at the 1995 Annual Meeting of the Society of Perinatal Obstetricians.
  22. Early vs Late Amniotomy for Labor Induction: A randomized Trial. Mercer B, McNanley T, O'Brien JM, Sibai BM. Presentation to the 1995 Annual Meeting of the Society of Perinatal Obstetricians.
  23. Is Daily Antenatal Testing in Patients with Severe Preeclampsia Excessive? Chari RS, Friedman SA, O'Brien JM, Sibai BM. Presentation to the 1995 Annual Meeting of the Society of Perinatal Obstetricians.
  24. The Impact of Initiating an HIV Screening Program. Lewis R, O'Brien JM, Ray D, Sibai BM. Presentation to the 1995 Annual Meeting of the Society of Perinatal Obstetricians.
  25. A Comparison of Cervicovaginal Fetal Fibronectin and Prolactin for the Prediction of Premature Delivery in Asymptomatic Women.
JOHN ROBERT BARTON, M.D.
 Dr. Barton
Business Address
Office Central Baptist Hospital
Perinatal Diagnostic Center
1740 Nicholasville Road
Lexington, KY 40503
(859) 260-6970
Education
1975-1979 Centre College of Kentucky, B.S. (1979)
1979-1981 University of Kentucky Graduate School, M.S. (1985)
1981-1985 University of Kentucky College of Medicine, M.D. (1985)
Appointments:
1985-1986 Internship University of Kentucky Obstetrics and Gynecology
1986-1989 Residency University of Kentucky Obstetrics and Gynecology
1989-1991 Fellowship University of Tennessee at Memphis Maternal-Fetal Medicine
1991-present Director, Maternal-Fetal Medicine Central Baptist Hospital Lexington, Kentucky
1995-1997 Assistant Clinical Professor of Obstetrics and Gynecology University of Louisville
1996-present Assistant Professor of Obstetrics and Gynecology Community-Based Faculty University of Kentucky
1997-present Associate Clinical Professor of Obstetrics and Gynecology University of Louisville
2000-present Volunteer Professor of Obstetrics and Gynecology University of Cincinnati
Certification
1986 National Board of Medical Examiners, Diplomate
1992 American Board of Obstetrics and Gynecology
1994 American Board of Obstetrics and Gynecology
1988 Maternal-Fetal Medicine subspecialty American Registry of Diagnostic Medical Sonographers #20335
Editorial Consultant
1988 American Journal of Obstetrics and Gynecology
1988 Obstetrics and Gynecology
1981 The Journal of Maternal-Fetal Medicine
1981 Journal of Perinatology
Society Membership
1988 Fellow, American College of Obstetricians and Gynecologists Society of Maternal-Fetal Medicine
1988 North American Society for the Study of Hypertension in Pregnancy Executive Committee (2000-present)
1981 International Society for the Study of Hypertension in Pregnancy
1981 John W. Greene, Jr. Gynecological Society
1981 Executive Committee (1987-1989, 1991-present)
1981 Vice-president (1991-1992, 1999-present)
1981 President-elect (1992-1994)
1981 President (1994-1995)
Organizational Activities
1997-present American Board of Obstetrics and Gynecology Examiner
Honors and Awards

Central Association Award

Central Association of Obstetricians and Gynecologists, 63rd Annual Clinical Meeting

Hepatic Imaging in HELLP Syndrome

Best Oral Presentation Fellows Plenary Session

Society for Maternal Fetal Medicine, 20th Annual Meeting

Maternal and Fetal Genetic Thrombophilias are not Associated with Severe Preeclampsia

Layfayette High School Alumni Hall of Fame Induction - July 2000
State Committees
1994-present Kentucky Maternal Mortality Study Committee
1999-present KMA/KHA Anthem Case Severity Committee
Publications:Peer Reviewed Journals
  1. Barton JR, Heitt AK, O'Connor WN, Nissen SE, Greene JW Jr. Endomyocardial ultrastructural findings in preeclampsia. Am J Obstet Gynecol 1991;165:389-91.
  2. Barton JR, Rogers RC, Wilson DA, Whybrew LD, Sibai BM. Nifedipine pharmacokinetics and pharmacodynamics during the postpartum period in patients with preeclampsia. Am J Obstet Gynecol 1991;165:951-4.
  3. Mabie WC, Barton JR, Sibai BM. Adult respiratory distress syndrome in pregnancy. Am J Obstet Gynecol 1992:167:950-7.
  4. Dahmus MA, Barton JR, Sibai BM. Cerebral imaging in eclampsia: Magnetic resonance imaging versus computed tomography. Am J Obstet Gynecol 1992:167:935-41.
  5. Barton JR, Riely CA, Adamec TA, Shanklin DR, Khoury A, Sibai BM. Hepatic histopathologic condition does not correlate with laboratory abnormalities in HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count). Am J Obstet Gynecol 1992;167:1538-43.
  6. Barton JR, Bronstein SJ, Sibai BM. Management of the eclamptic patient. Journal of Maternal-Fetal Medicine 1992;1:31-9.
  7. Barton JR, Sibai BM, Whybrew WD, Mercer BM. Urinary endothelin-1: Not a useful marker for preeclampsia. Am j Obstet Gynecol 1993;168:599-601.
  8. Barton JR, Stanziano GJ, Sibai BM. Monitored outpatient management of mild gestational hypertension remote from term. Am J Obstet Gynecol 1994;170:765-69.
  9. Usta IM, Barton JR, Amon EA, Gonzalez A, Sibai BM. Acute fatty liver of pregnancy: An experience in the diagnosis and management of fourteen cases. Am J Obstet Gynecol 1994;171:1342-7.
  10. Barton JR, Stanziano GJ, Jacques DL, Bergauer NK, Sibai BM. Monitored outpatient management of mild gestational hypertension remote from term in teenage pregnancies. Am J Obstet Gynecol 1995;173:1865-8.
  11. Barton JR, Sibai BM. Hepatic imagining in HELLP syndrome (hemolysis, elevated liver enzymes, and low platelet count). Am J Obstet Gynecol 1996;174:1820-7.
  12. Barton JR, Bergauer NK, Jacques DL, Coleman SK, Stanziano GJ, Sibai BM. Does advanced maternal age affect pregnancy outcome in women with mild hypertension remote from term? Am J Obstet Gynecol. 1997;176:1236-43.
  13. Mabie WC, Barton JR, Sibai BM. Septic shock in pregnancy. Obstet Gynecol 1997;90:553-61.
  14. O'Brien JM, Milligan DA, Barton JR. Impact of high-dose corticosteroid therapy for patients with HELLP (hemolysis, elevated liver enzymes and low platelet count) syndrome. Am J Obstet Gynecol 2000;183:921-4.
  15. Barton JR, O'Brien JM, Bergauer NK, Jacques DL, Sibai BM. Mild gestational hypertension remote from term. Progression and outcome. AM J Obstet Gynecol 2001;184: in press.
Publications: Books Chapters and Reviews
  1. Barton JR, Sibai BM. Acute life threatening emergencies in preeclampsia-eclampsia. Hypertension in Pregnancy issue, Sibai BM (ed)/Clin Obstet Gynecol. 1992;35(2):402-413.
  2. Barton JR, Sibai BM. Care of the pregnancy complicated by HELLP syndrome. Gastrointestinal and Liver Problems in Pregnancy issue, Riely CA and Abell TL (ed)/Gastroenterology Clin North Am 1992;21(2):937-950.
  3. Barton JR, Sibai BM. Management of severe hypertension in pregnancy/eclampsia-USA. In Hypertension in Pregnancy, Walker JJ and Gant NF (ed), Chapman and Hall Medical, London, England, 1996 pp 281-309.
  4. Barton JR, Cystic fibrosis in pregnancy. In Principles and Practice of Medical Therapy in Pregnancy, 3rd Edition, Gleicher N et al (ed), Appleton & Lange, Norwalk, CT, 1998 pp 898-902.
  5. Barton JR, Sibai BM. HELLP and the liver disease of preclampsia. Pregnancy and Liver Disease issue, Riely CA(ed)/Clinics in Liver Disease. 1999;3(1):31-48.
  6. Barton JR, Witlin AG, Sibai BM. Management of mild preeclampsia. Hypertension and Pregnancy issue, Sibai BM (ed)/Clin Obstet Gynecol. 1999;42(3):455-69.
  7. Swayze CR, Barton JR, Skerman JH. Amniotic fluid embolism. Seminars in Anesthesia, Perioperative Medicine and Pain. 2000;19(3):181-7.
  8. Barton JR, Sibai BM. HELLP Syndrome, In Hypertensive Disorders in Women, Sibai BM (ed), W.B. Saunders, in press, 2000.
Selected Abstracts
  1. Management and outcome of pregnancies complicated by HELLP syndrome: A community hospital perspective. Barton JR, O'Brien JM, Milligan DA. XIIth World Congress on Hypertension in Pregnancy, Paris, France, July 2000. (Hypertension in Pregnancy 2000;19 [supp 1]:151)
  2. HELLP (hemolysis, elevated liver enzymes and low platelet count) syndrome versus severe preeclampsia: Onset at < 28.0 weeks' gestation. haddad b, barton jr, livingston jc, chahine r, sibai bm. xiith world congress on hypertension in pregnancy, paris, france, july 2000. (hypertension in pregnancy 2000;19 [supp 1]:58)
  3. Risk factors for adverse maternal outcome in women with HELLP (hemolysis, elevated liver enzymes and low plate count) syndrome. Haddad B, Barton JR, Livingston JC, Chahine R, Sibai BM.XIIth World Congress on Hypertension in Pregnancy, Paris, France, July 2000. (Hypertension in Pregnancy 2000;19 [supp 1]:96)
  4. The impact of high dose corticosteroid on laboratory changes in women with hemolysis, elevated liver enzymes and low platelet count (HELLP syndrome). Barton JR, Bush K, O'Brien JM, Milligan DA. XIIth World Congress on Hypertension in Pregnancy , Paris, France, July 2000. Hypertension in Pregnancy 2000;19 [supp 1]:144)
  5. The impact of corticosteroid administration on the rate of regional anesthesia in patients with hemolysis, elevated liver enzymes and low platelet count (HELLP syndrome). Barton JR, Shumate SA, O'Brien JM, Stachwell SL, Milligan DA. XIIth World Congress on Hypertension in Pregnancy, Paris, France, July 2000. (Hypertension in Pregnancy 2000;19 [supp1]:148)
  6. Tumor necrosis factor alpha polymorphisms, plasma levels, and severe preeclampsia. Livingston JC, Park V, Barton JR, Haddad B, Crouse D, Elfering S, Quasney M, Mabie B, Sibai BM. XIIth World Congress on Hypertension in Pregnancy, Paris, France, July 2000. (Hypertension in Pregnancy 2000;19 [supp 1]:101)
  7. Long-chain 3 hydroxyacyl-CoA dehydrogenase deficiency is uncommon in pregnancies complicated by full/partial HELLP syndrome or acute fatty liver of pregnancy. Livingston JC, Barton JR, Park V, Haddad B, Mabie WC, Sibai BM. Society for Maternal-Fetal Medicine, 21st Annual Meeting, Reno, NV, February 2001. (Am J Obstet Gynecol 2001;184;[1 (pt2)]:S73)
  8. Maternal and fetal inherited thrombophilias and preterm birth. Livingston JC, Barton JR, Park V, Haddad B, McKinney E, Sibai BM. Society for Maternal-Fetal Medicine, 21st Annual Meeting, Reno, NV, February 2001. (Am J Obstet Gynecol 2001;184:[1(pt2)]:S109.
  9. Subsequent pregnancy outcomes in women with a history of HELLP syndrome < 30 weeks. mckinney e, haddad b, barton jr, livingston jc, sibai bm. society for maternal-fetal medicine, 21st annual meeting, reno, nv, february 2001. (am j obstet gynecol 2001;184[1(pt2)]:s79)
  10. Diurnal variation in blood pressure and subsequent relation to outcomes in women with gestational hypertension. Saade G, Barton JR, Jacques DL, Bergauer NK, Stanziano GJ, Sibai BM. Society for Maternal-Fetal Medicine, 21st Annual Meeting, Reno, NV, February 2001. (Am J Obstet Gynecol 2001;184:[1(pt2)]:S82.
  11. Mild gestational hypertension: Racial differences are associated with altered outcomes in women undergoing outpatient management. Barton JR, O'Brien JM, Barton CB, Bergauer NK, Jacques DL, Sibai BM. Society for Maternal-Fetal Medicine, 21st Annual Meeting, Reno, NV, February 2001. (Am J Obstet Gynecol 2001;184:[1(pt2)]:S79)
  12. The utility of umbilical artery Doppler investigation in women with the syndrome of hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome). Bush K, O'Brien JM, Barton JR. American Institute of Ultrasound in Medicine, 45th Annual Meeting, Orlando, FL, March 2001.
Research In Progress
Monitored outpatient management of mild preeclampsia remote from term.

Longitudinal assessment of hypertension in multifetal pregnancies.

The assessment of ultrastructural, genetic and biochemical abnormalities in pregnancies complicated by preeclampsia and eclampsia.

The assessment of platelet abnormalities in pregnancies complicated by HELLP syndrome.

Neonatal outcome in pregnancies complicated by severe preeclampsia remote from term.
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