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Neurology & Stroke Research



Research is one of the components that make us unique at Baptist Health Lexington.  Our highly trained staff is dedicated to providing the latest innovations and newest therapies in a community-based setting.  We are working to improve the lives of our stroke and neurological patients.

Below is a listing of current stroke/neurology clinical trials:

IRB# 555 CREST closed to enrollment in follow up:
Randomized trial for carotid revascularization by endarterectomy or stenting.  

Patients that were eligible could not be high risk for surgery. Could be either symptomatic or asymptomatic.

Will be followed for up to 10 years.

IRB#  843 ACT 1:
Asymptomatic carotid stenosis stenting versus endarterectomy TRIAL- “the ACT 1 Study”.

A randomized trial to demonstrate the non-inferiority of carotid artery stenting using the the Xact ® Carotid stent system to carotid endarterectomy for the treatment of asymptomatic extracranial carotid stenotic disease. A randomized trial.

Asymptomatic, defined as no stroke or TIA within 180 days prior to procedure. Have a discrete lesion located in the internal carotid artery (ICA); the contiguous common carotid (CCA) artery may be involved.Carotid stenosis >70% and < 99% by carotid ultrasound or angiogram without significant > 60% of the ICA/CCA contralateral stenosis.

For additional info please contact Linda Breathitt or Sara Birk 859-260-6344.

IRB# 1025 The Stanford Registry:

This study that collects routine clinical data and outcomes of patients who have intracranial stents placed for treatment of intracranial aneurysms. This data is being collected in an effort to determine if differences in outcomes are observed based on routine drug dosing and testing.

For additional information please contact Linda Breathitt or Sara Birk at 859-260-6344.

 IRB# 1080 SWIFT:

A global, multi-center, two-arm, prospective, randomized, open, blinded endpoint IDE study to determine if subjects experiencing an acute ischemic stroke due to a large vessel occlusion, treated with combined IV TPA and Solitaire FR (mechanical thrombectomy intervention) within 6 hours of symptom onset have less stroke related disability than those subjects treated with TPA alone. Patients will be followed for 90 days.

For additional information please contact Linda Breathitt or Sara Birk at 859-260-6344.

IRB# 1076 Aspire:

A global multi-center single arm observational registry, for patients who have had a brain aneurysm (a bulge in a blood vessel in your head) that requires or will require a surgical procedure with the  Pipeline Embolization Device or PED which is placed in the artery where the aneurysm occurred. The PED is an approved device. This means that the device was approved for use in the United States, countries in Europe, and other areas of the world.

 A research registry collects information from your medical records in order to analyze the data.  Past, current and future medical information about your treatment of the brain aneurysm will be collected. By collecting the medical information about many patients, such as you, with a brain aneurysm, researchers will be able to increase their knowledge about neurovascular disease. Neurovascular disease is a disease that affects both the nerves and the blood vessels.  Patients will be followed for 60 months.

For additional information please contact Linda Breathitt or Sara Birk at 859-260-6344.